Wide receiver Brandon Aiyuk will not return to practice this week. Coach Kyle Shanahan said Monday on a conference call with ...

The San Francisco 49ers started the trade deadline carousel early, swinging a deal with the New England Patriots for ...

Throw out any hypotheticals of the 49ers possibly trading this player, as Kyle Shanahan essentially shut down the notion.

Key offensive and defensive stars sidelined. The 49ers' depth faces its biggest test yet as crucial players fight through ...

The San Francisco 49ers have had several injuries to key players through the first few weeks of the 2025 season, and that's led to some constant changes to their practice squad to keep things going.

The star wideout had been very visible during practice throughout training camp and early this season, running alongside his fellow receivers during the open portion of practice, with his speed and ...

Making Aiyuk’s absence worse is two wideouts, Ricky Pearsall Jr. (knee) and Jauan Jennings (knee, shoulder, ribs), have also ...

Brock Purdy returns to the field after a two-week absence but 49ers have to settle for field goals after getting into the red ...

The 49ers’ remaining schedule would be challenging even with Fred Warner and Nick Bosa. Without them? Good luck.