Recombinant adeno-associated virus (AAV) vectors are predominantly nonintegrating, but rare genomic integration events have been associated with oncogenesis in neonatal murine models. Here we ...

(A) Generation of the novel AAVT42 vector by directed evolution and in vivo screening. The cap genes of AAV1, AAV2, AAV3B, AAV4, and AAV6-9 were mixed, after digestion, denaturation, and reannealing, ...

While there is no cure for ANCA-associated vasculitis (AAV), treatment is usually very effective at bringing it under control and preventing life-threatening complications. This group of rare ...

Age-related macular degeneration (AMD) is the leading cause of blindness among older adults. The exudative or ‘wet’ form of the disease is characterized by the growth of abnormal blood vessels from ...

4D Molecular Therapeutics (NASDAQ:FDMT) executives said the company is seeing strong clinical trial momentum for its lead ...

Adeno-associated viruses (AAV) have emerged as pivotal delivery vehicles for gene therapy due to their overall safety (less immunogenic), efficiency (broad tropism), and long-term gene expression.

Researchers at National Taiwan University have developed a liver-directed IL-10 gene therapy that strengthens cancer-fighting ...

HydroGene Therapeutics is a biotechnology company creating accessible gene therapies for all liver diseases. HydroGene is ...