Nuclear magnetic resonance (NMR) spectroscopy has long been indispensable for probing the structural and dynamic properties of amide bonds, which underpin peptide function, solvent behaviour and ...
Nature typically outdoes chemists when it comes to efficiently carrying out reactions. But for a nickel—or make that a simple nickel catalyst—a team of UCLA chemists has matched wits with enzymes on ...
Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...
Osaka University group demonstrates a catalyst that effectively converts amides to amines at low temperature under low hydrogen pressure Amines are vital in nature; for example, amino acids—the ...
A team at UNC-Chapel Hill has developed a new process for synthesizing amides in a 100% atom-economical, sustainable fashion using Earth-abundant, environmentally friendly cobalt. UNC-Chapel Hill ...
The Silent Skeleton of Modern Medicine Amide bonds are the "bread and butter" of medicinal chemistry. These molecular linkages form the structural backbone of some of the world's most successful drugs ...
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