In the absence of large RCTs comparing TMT versus RC for MIBC, investigators conducted a systematic review and meta-analysis.

"We found CKD to be independently associated with a higher likelihood of nonorgan confined disease and lymph node metastases as well as postoperative transfusion and 90-day readmissions." – Nguyen, et ...

PATIENTS AND METHODS: All patients undergoing radical cystectomy with bilateral pelvic iliac lymphadenectomy, with the intent to cure, for transitional-cell carcinoma of the bladder between July 1971 ...

On Tuesday, the U.S. Food and Drug Administration (FDA) approved Johnson & Johnson's (NYSE:JNJ) Inlexzo (gemcitabine ...

"The main strength of this study is the use of a nationwide population-based cohort encompassing nearly all patients with bladder cancer undergoing RC over 8 years, with detailed clinicopathological, ...

Prophylactic tranexamic acid showed no reduction in blood transfusion rates in open radical cystectomy patients. The trial found no significant differences in secondary outcomes, including estimated ...

The U.S. FDA has approved Johnson & Johnson's INLEXZO (gemcitabine intravesical system) for adults with BCG-unresponsive ...

Approval was based on data from the Phase IIb SunRISe-1 trial (NCT04640623), in which Inlexzo demonstrated an 82% complete ...

The novel formulation of the stalwart chemotherapeutic drug gemcitabine, which allows it to be administered directly into the ...