Before we get to the latest rankings, let’s catch up with the latest ESPN playoff odds for the Bills in four key metrics. A positive development here, Buffalo moves back up the ladder, now at three. People may have panned the Bills’ win against a seemingly hapless Steelers group, but the win was important to Buffalo’s postseason hunt.

ESPN's computer model has made its pick for the Buffalo Bills at Houston Texans game on Thursday evening. Week 12 of the 2025 NFL regular season is set to kick off on Thursday night. It'll start with a game between two AFC foes.

Bills will aim to control the clock and slow Joe Burrow as Bengals bring passing firepower to Week 13 matchup.

With the four weekday games from last week's holiday slate, your Week 14 NFL predictions should account for the rest advantages that teams have. Games like Bengals vs. Bills (-5.5), Ravens vs. Steelers (+6),