How cells control gene expression by cleaning up their mistakes Date: September 6, 2024 Source: University of Chicago Summary: New research suggests that alternative splicing may have an even ...

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene ...

As an example of such structures, which play an important role in the initiation of translation and thus in the regulation of gene expression, the Bonn researchers have now investigated internal ...

Epigenetics and Heritable Control of Gene Expression The epigenome regulates nearly every process in the human body. By studying epigenetics, scientists have revealed some secrets to aging, cancer, ...

Timothy Frei, Ching-Hsiang Chang, Maurice Filo, Asterios Arampatzis, Mustafa Khammash, A genetic mammalian proportional–integral feedback control circuit for robust and precise gene regulation, ...

Other major regulators of gene expression—including proteins involved in stress responses, stem cell maintenance and cancer progression—also rely on beta-catenin to link up with BAF.

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

To overcome these limitations, research has shifted to inducible promoters such as the glucocorticoid-inducible system, allowing precise control of gene expression in plants.