Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid ...
Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...
The FDA approved darolutamide for mHSPC on June 3, [2025], so we now have this in our armamentarium, along with all the other ...
A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, ...
A new study has revealed the mechanism of multimerization — the association of different molecules to form complex structures — of the glucocorticoid receptor, a process critical to its physiological ...
A Hybrid Type III Effectiveness-Implementation Trial to Optimize Medication Safety With Oral Antitumor Therapy in Real-World: The AMBORA Competence and Consultation Center Androgen receptor pathway ...
Deciphering how the GR forms oligomers—through the binding of several subunits—opens a crucial avenue for developing more ...
Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...
Wellbutrin can interact with several drugs, including other antidepressants, stimulants, and certain diabetes medications. These interactions can increase the risk of side effects or reduce the ...