PharmTech

Determining the Best Estimate of Probability of Passing Multiple Stage Tests: Part 2—Dissolution

Pramote Cholayudth, [email protected], is the founder and manager of PM Consult. He is an industrial pharmacist with more than 40 years of experience. He is a guest speaker on process validation to ...
Risk

Estimating long-run probability of default, asset correlation and portfolio-level probability of default using Vasicek models

In this paper, we propose Vasicek-type models for estimating portfolio-level probability of default (PD). With these Vasicek models, asset correlation and long-run PD (LRPD) for a risk-homogeneous ...
PharmTech

Determining the Best Estimate of Probability of Passing Multiple Stage Tests: Part 1–Content Uniformity

Pramote Cholayudth is an industrial pharmacist with more than 40 years of experiences. He is a guest speaker on Process Validation to industrial pharmaceutical scientists organized by Thailand’s FDA.
ascopubs.org

Updated survival-based analysis using inverse probability of censoring weighted analysis (IPCW) to estimate the cost-effectiveness of letrozole and anastrozole versus tamoxifen ...

Background: The latest update of the BIG 1-98 study (74 months) applied IPCW to estimate treatment effect in the presence of selective crossover (25% of TAM pts). The IPCW hazard ratio for overall ...
The Irish Times

'Risk intelligence' site opens

RESEARCH IS underway to try to measure people’s “risk intelligence” their ability to gauge probability and anticipate levels of risk. Having the skill might make you a successful gambler, but is also ...