Graphic shows the sequence of events in the fracture repair process: innervation (nerve fiber growth and supply), vascularization (blood vessel growth and supply), ossification (production of ...

Orthopedic implants are used to fixate the bone fragments of fractures. Novel smart implants are now being developed that can continuously monitor and actively promote bone healing—by, for example, ...

Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies Apex1 as a redox-regulated driver of fracture repair. Using genetic mouse ...

The study uncovers a unique reparative function of regulatory T cells (Tregs) in the process of fracture healing, a discovery that adds a new dimension to our understanding of the immune response in ...

Bone has an extraordinary capacity to heal after injury, restoring its structure and mechanical function without leaving a scar. Yet for a clinically significant number of patients, this regenerative ...

A medical research team at Saarland University, led by Professor Bergita Ganse, has discovered a new approach to monitoring bone fracture healing by measuring blood supply to the tissue at the ...

Researchers uncover a redox-regulated mechanism that determines whether bone fractures heal or progress to non-union. Bone has an extraordinary capacity to heal after injury, restoring its structure ...

The first comprehensive single-cell atlas of bone-innervating sensory neurons has identified their dual role in reporting and repairing bone damage, providing a potential target for drugs that might ...