A recent study, led by Professor Wu (Wenzhou Institute University, Wenzhou Medical University) and Professor Huang (Northeastern University), explores liquid–liquid phase separation (LLPS), a ...
Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...
BACKGROUND: Congenital heart disease (CHD), the most common birth defect and a leading cause of infant mortality, is ...
The dynamic internal fluidity of nuclear MORC2 condensates, rather than their mere assembly, is strictly required for transcriptional regulation and is selectively disrupted by neuropathy-linked ...
Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered ...
LLPS as a rising molecular entity in the cytoplasm regulates diseases progression via a variety of ways. For example, the relationship between LLPS and cancer can be summarized into six aspects: gene ...
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