For patients with gout exacerbations while on pegloticase (Krystexxa), adding methotrexate may help reduce uric acid levels, researchers suggested at the European League Against Rheumatism (EULAR) ...

Subcutaneous tocilizumab, alone or with methotrexate, showed superior efficacy over methotrexate monotherapy in treating rheumatoid arthritis in Chinese patients. The trial demonstrated higher ACR20 ...

plaque psoriasis The efficacy, safety, pharmacokinetics, and immunogenicity of adalimumab combined with MTX compared with that adalimumab in patients with chronic plaque psoriasis is evaluated. Adding ...

Charlotte, NC and Mobile, AL - The new antifolate CH-1504 (Chelsea Therapeutics, Charlotte, NC), formerly known as MobileTrex or M-Trex, does not give rise to the polyglutamated and hydroxylated ...

A second course of methotrexate, the most commonly used drug to treat rheumatoid arthritis, is effective in nearly half of studied patients for whom a previous treatment with the drug was ineffective.

Researchers conducted an open-label randomized trial across multiple centers in China to evaluate the efficacy of MMF combined with methotrexate in treating Takayasu arteritis. They included 111 adult ...

Antares Pharma announced that the FDA has approved Otrexup (methotrexate) injection, the first subcutaneous (SC) methotrexate for once-weekly self-administration with a single-dose, disposable ...