The discovery of macrocyclic peptide therapeutics has been slow. We introduce RFpeptides, a deep learning method that enables the de novo design of macrocyclic peptide binders to therapeutic targets.
By combining CRISPR knock-in with small peptide tags, researchers can study proteins in their native cellular context, ...
Peptide-based strategies offer promising solutions to overcome the complex, multi-tissue barriers of osteoarthritis. Their tunability, specificity, and versatility enable targeted drug delivery to ...
This schematic illustrates the AI-powered pipeline for designing novel antimicrobial peptides (AMPs). Through sequence and structure modeling, AI models enable rational design and de novo generation ...
A peptide that successfully targeted and killed metastatic cancer cells in mice may open the door to developing more efficient ways to detect and treat metastatic breast cancer in humans, UTHealth ...
A peptide that successfully targeted and killed metastatic cancer cells in mice may open the door to developing more efficient ways to detect and treat metastatic breast cancer in humans, UTHealth ...
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