Conclusion We were unable to identify any modifiable factor present in population-based observational studies that improved agreement with randomized trials. There was no agreement beyond what is ...

Data regarding the effect of radiotherapy on mortality in patients with breast cancer diverged widely between randomized clinical trials and observational data, even after adjustment for potential ...

The GRACE principles lay out 3 questions to help healthcare providers, patients, and other decision makers evaluate the quality of noninterventional comparative effectiveness studies.

Randomized controlled trials are time-consuming and expensive, but well-designed ones are more effective at minimizing bias than most other types of studies.

This review article considers the strengths and weaknesses of randomized clinical trials that are conducted through the analysis of data gathered by health insurers.

GLP-1a treatment in patients with polycythemia vera was linked to significant reductions in mortality, disease progression, and serious complications.

The gold standard eating pattern has been tied to a slower rate of cognitive decline and a lower dementia risk ...