Antidepressants treat symptoms of depression by increasing levels of brain signaling molecules (neurotransmitters) such as serotonin, as with the most widely used type of antidepressant, selective ...

Antidepressant therapies modulate monoaminergic neurotransmission, principally via serotonin, noradrenaline and dopamine pathways. Classes include selective serotonin reuptake inhibitors (SSRIs), ...

SSRI mechanism: SSRIs block serotonin reuptake, increasing levels that help regulate mood, sleep, and appetite. Potential risks: Side effects can include temporary anxiety increases and rare severe ...

A new study from Karolinska Institutet shows that different SSRI medications affect metabolic processes in developing nerve cells in distinct ways. Alterations in energy metabolism, oxidative stress ...

Antidepressants and certain antidiarrheal drugs are linked to a slightly higher risk for death for adults with irritable bowel syndrome.

Hypobaric hypoxia, the reduced oxygen pressure encountered at high altitudes, has emerged as a paradoxical stimulus with potential antidepressant properties. Experimental models reveal that controlled ...

When it comes to psychological problems, there are different ways how they can be managed. Talk therapies, such as psychodynamic or cognitive-behavioral therapy, as well as antidepressants like ...

Major depressive disorder (MDD) is among the most common psychiatric disorders, affecting approximately 330 million people worldwide. This disorder is characterized by persistent feelings of sadness, ...

Researchers tested liraglutide in stress models. The GLP-1 therapy reduced depression-like behaviors via gut microbiome ...