Researchers discovered that a protein called AP2A1 acts as a master switch controlling whether cells behave young or old When ...

A new study shows how the molecule Sox9 is involved in a positive feedback loop that accelerates the aging of blood vessels, which could be used as a target for new therapies. "By unraveling the ...

Kidney fibrosis, a common endpoint of chronic kidney disease (CKD), is strongly linked to aging, with cellular senescence emerging as a key driver in its pathogenesis. This overview synthesizes ...

Cellular senescence—an irreversible cell-cycle arrest coupled with the production of pro-inflammatory secretions known as SASP—is now viewed as a central driver of musculoskeletal aging. Accumulation ...

In a recent study published in Nature Metabolism, researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis. Fibrogenesis is a defensive reaction to ...

Edward Bullmore explores the strong connection between inflammation and mental illness in his book, The Inflamed Mind. The book discusses several key points, including the role of the immune system in ...