Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from ...

Many patients suffer from epilepsy that cannot be controlled by current medications. Surgical removal of epileptogenic brain regions is effective in only about half of cases, and not all patients are ...

Boosting KCC2 function reduced seizures and abnormal brain activity in temporal lobe epilepsy models. Learn how this strategy could aid drug-resistant epilepsy.

Researchers identify prochlorperazine as a potential new treatment for temporal lobe epilepsy by restoring the KCC2 chloride ...

Epilepsy is a neurological condition characterised by recurrent episodes of seizures. Most cases of epilepsy do not have a clear cause. The primary pathogenesis of many forms of epilepsy is an ...

UAB Department of Neurosurgery Professor Kristen Riley, M.D., and Neurosurgery PGY6 Resident Adeel Ilyas, M.D., are among the authors of a recent paper published in NEJM Evidence titled, “Pro-Ictal ...

The present study was designed to evaluate the genetic mechanisms in patients with focal epileptiform discharges in the mid-temporal or central regions, an electroencephalographic abnormality of high ...

Epilepsy surgery has been shown to be an effective treatment for patients with intractable epilepsy. The only randomized controlled trial conducted in this setting to date found a dramatic advantage ...

What can be done to control unprovoked seizures in a 55-year-old woman with drug-resistant epilepsy who was admitted to the hospital? The patient's medical history indicated that she had been ...