Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports.

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Imprinting is yet another process involved in eukaryotic gene regulation; this process involves the silencing of one of the two alleles of a gene for a cell's entire life span.

Single-cell proteomics with RNA sequencing uncover hidden gene expression dynamics in stem cell differentiation.

Both systemic sclerosis and systemic lupus erythematosus have down-regulated RGS5, but they also have distinctive genetic expression profiles.

The discovery of distinct basal and induced gene activity in different nerve cells opens up new possibilities for treatment.