PR+ breast cancer responds well to hormone therapy, underscoring the need for molecular insight and targeted treatment ...

Maternal stress is a major risk factor for preterm birth (PTB), with recent mouse studies highlighting the role of FKBP51 in stress-induced PTB. This study identifies the 15dPGJ2-mediated inhibition ...

Discover why some women develop fibroids while others don't, from genetics and hormones to lifestyle and environmental ...

Up to 80% of women develop fibroids by the age of 50. Fibroids are non-cancerous smooth muscle tumors. They are characterized ...

Triple-positive breast cancer is a type of breast cancer that tests positive for estrogen receptors, progesterone receptors, and high levels of HER2 protein. Some types of breast cancer cells use ...

As genetic and biomarker tests become more common, so do new therapies that target specific tumor types and may lead to ...

It would be short-sided, erroneous and dangerous to think ill of mifepristone, which has several important applications,, M.D ...

hypokalemia or QT prolongation – serious adverse events that can arise in patients taking currently approved medications – ...

Corcept Therapeutics (CORT) announced that the FDA filed its New Drug Application (NDA) submission for its proprietary, selective cortisol ...

MR = Mineralocorticoid receptor; PR = Progesterone receptor. The relative binding affinity (%) of the main progestins discussed in this paper for the different steroid receptors is indicated.