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Primary Cancers Known to Metastasize to the Liver Categorized by Origin — Gastrointestinal vs. Extra-Gastrointestinal In my exam, there was a question asking: “Which cancer does not metastasize to the liver? Prostate cancer can metastasize to the liver — but it is uncommon.It’s not the usual or early site of spread. Most common sites for Prostate cancer Metastasis is Bone (osteoblastic) ,Lymph nodes and Lungs Liver involvement Occurs late, typically in advanced or castration-resistant prostate c
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