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Cancer Apoptosis! Image of the Week - October 29, 2018 With apologies for cross posting. CIL:50503 - http://www.cellimagelibrary.org/images/50503 Description: Apoptosis human melanoma cancer cell. Author: Lisa Pollaro Licensing: Copyrighted. This image is copyright protected. Any public or private use of this image is subject to prevailing copyright laws. Please contact the content provider of this image for permission requests. | Cell Image Library
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Draw the following apoptotic pathway, which operates in human immune cells. A death signal is received when a molecule called Fas binds its cell-surface receptor. The binding of many Fas molecules to receptors causes receptor clustering. The intracellular regions of the receptors, when together, bind proteins called adaptor proteins. These in turn bind to inactive molecules of caspase- 8, which become activated and then activate caspase-3. Once activated, caspase-3 initiates apoptosis. | Numerad
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